

Leaders in Research![]()
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| Angela L. Jefferson, PhD Associate Professor of Neurology Alzheimer's Disease Clinical and Research Program Boston University School of Medicine
Dr. Angela Jefferson is an Assistant Professor of neurology at the Boston University School of Medicine. She is the Co-Director of the Education & Information Transfer Core at the University’s Alzheimer’s Disease Center and Director of Predoctoral Training for the Alzheimer’s Disease Clinical & Research Program. Dr. Jefferson’s primary research focuses on uncovering vascular risk factors for abnormal cognitive aging, including mild cognitive impairment and Alzheimer's disease. In particular, she is interested in the relationship between abnormalities in the contracting of the heart (systolic dysfunction) and neuropsychological and neuroimaging markers of maladaptive brain aging. Dr. Jefferson is currently working with colleagues at the Boston University Alzheimer’s Disease Center and Center for Biomedical Imaging to examine how systolic function relates to white matter integrity and cognitive progression among older adults with mild cognitive impairment. She is also relating cardiac structure and systolic function variables to structural brain MRI and cognitive markers in the Framingham Heart Study Offspring Cohort. Finally, Dr. Jefferson is collaborating with colleagues at the New England Centenarian Study to study the relations between systolic function and cognition among adult offspring of centenarians. Dr. Jefferson received her PhD in clinical psychology/neuropsychology from Drexel University in Philadelphia. She completed a clinical internship at Brown Medical School in neuropsychology, and two post-doctoral fellowships—one at the Clinical Psychology Training Consortium, Department of Psychiatry & Human Behavior, Brown Medical School, and another at the Alzheimer’s Disease Center, Department of Neurology, Boston University School of Medicine. | |
| Primary Research (for Beeson Program): Cardiac integrity and the Aging Brain
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